Medications to Treat Anxiety Therapy is the best way to manage anxiety, however sometimes a short-term course of medication may be necessary. Antidepressants and tranquilizers are two of the medications that can be used to treat anxiety. SSRI antidepressants, such as citalopram (Celexa), Escitalopram (Lexapro) and sertraline (Zoloft), improve the
